I’ve had the pleasure of treating a number of patients by now who have started their weight loss journey with Semaglutide. Its most notable effect, reduction of appetite, is the first effect of the medication people discover. However, in my time observing these patients, I have noticed another pleasant, unintended benefit of the drug: Its effect on alcohol use and compulsive behavior.
Yes, the medication seems to lower the desire for alcohol.

Beyond Calories: Semaglutide and Alcohol Use

Unexpectedly, many patients reported a diminished desire for alcohol after beginning their treatment with Semaglutide. When it comes to losing weight, alcohol can be the bane of our patients’ existence. The “empty calories” without any added nutritional benefit will most certainly slow down attempts at weight loss.

The Ripple Effect of Reducing Alcohol Intake

When one has reached a point where they want to pursue healthier ways of living, cutting down or quitting alcohol is another great way to improve overall health. As we get older, we do not metabolize alcohol as effectively, and as a result, its negative effects seem to magnify. This includes poor sleep quality, longer and more severe hangovers, and worse overall mental health.

Beyond just weight loss, alcohol reduction has a huge impact on our overall quality of life.

Semaglutide's Influence on Alcohol Cravings and Mental Health

While semaglutide is not specifically indicated for the treatment of alcohol use disorders, some studies have explored the potential impact of GLP-1 receptor agonists, including semaglutide, on alcohol consumption. These studies suggest that these medications may have a modulating effect on the reward system in the brain, which could potentially influence alcohol intake.

The scope of Semaglutide's impact extends beyond appetite suppression, embracing a broader spectrum of health benefits. As more research unfolds on these novel medications, I do believe we will find out more of their promising effects.

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Daniel Kazmierski, MD

TeleFitMD Provider